Propofol-induced euphoria
Conditions
Interventions
Group B:Maintain the Narcotrend index within stage B0 to B2 (corresponding to an index range of 80–94).
Group C:Maintain the Narcotrend index within stage C0 to C2 (corresponding to an index range of 65-79).
Group D:Maintain the Narcotrend index within stage D0 to D1 (corresponding to an index range of 47-64).
Sponsors
Peking University Third Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1.Age: 18 to 65 years old; 2. Body mass index (BMI) is between 18 and 30 kg/m ²; 3. American Society of Anesthesiologists (ASA) grade I to III, with no serious heart or lung systemic diseases; 4. It is planned to undergo elective lower limb surgery and receive intraspinal anesthesia. 5. It is planned to return to the general ward after the operation
Exclusion criteria
Exclusion criteria: 1.Allergic to propofol; 2. There is preoperative cognitive dysfunction or language communication disorder; 3. Long-term use of sedative, anti-anxiety or antidepressant drugs; 4. Pregnant or lactating women; 5. Have a history of hearing impairment or motion sickness
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of (propofol-induced) euphoria; | — |
Secondary
| Measure | Time frame |
|---|---|
| Alterations in EEG features;Postoperative patient satisfaction; | — |
Countries
China
Contacts
Public ContactXu Mao
Peking University Third Hospital
Outcome results
None listed