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Study on the Pathophysiological Mechanisms of Microglial Activation in Perihematomal Edema Formation Following Intracerebral Hemorrhage

Study on the Pathophysiological Mechanisms of Microglial Activation in Perihematomal Edema Formation Following Intracerebral Hemorrhage

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500115553
Enrollment
Unknown
Registered
2025-12-29
Start date
2025-12-31
Completion date
Unknown
Last updated
2026-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Intracerebral Hemorrhage

Interventions

Sponsors

Beijing Tiantan Hospital, Capital Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 85 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria for patients with cerebral hemorrhage: 1. Spontaneous cerebral hemorrhage confirmed by head CT, including intracerebral hemorrhage and intraventricular hemorrhage, and treated with conservative therapy, craniotomy for hematoma evacuation or minimally invasive surgery; 2. Age >= 18 years and = 18 years and <= 85 years; D. Obtained informed consent.

Exclusion criteria

Exclusion criteria: Exclusion criteria for patients with cerebral hemorrhage: 1. Severe illness or special reasons (such as contrast agent allergy, stent placement, pacemaker placement, etc.) that prevent completion of imaging examinations; 2. Coexisting other major diseases (malignant tumors, severe chronic diseases, etc.); 3. Cerebral hemorrhage caused by head trauma cannot be excluded; 4. Pregnant or in the perinatal period. Exclusion criteria for the control group: 1. Coexisting other major diseases (malignant tumors, severe chronic diseases, etc.); 2. Pregnant or in the perinatal period; 3. Refusal to participate in this study.

Design outcomes

Primary

MeasureTime frame
Modified Rankin Scale;

Secondary

MeasureTime frame
Modified Rankin Scale;Perihematoma edema changes;Case fatality rate;All-cause mortality rate;

Countries

China

Contacts

Public ContactJunmei Wang

Beijing Tiantan Hospital, Capital Medical University

wwwjjjmmm1180@sina.com+86 136 2111 8672

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026