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Screening and identification of biomarkers for differentiating benign and malignant pulmonary nodules using multi-omics technologies

Screening and identification of biomarkers for differentiating benign and malignant pulmonary nodules using multi-omics technologies

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500115550
Enrollment
Unknown
Registered
2025-12-29
Start date
2023-04-11
Completion date
Unknown
Last updated
2026-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pulmonary Nodules

Interventions

Pulmonary Nodules Group:Not Available

Sponsors

Taizhou Central Hospital (Taizhou University Hospital)
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Age between 18 and 80 years; 2. Imaging (CT) indicating pulmonary nodules or pulmonary lesions (radiological features suggestive of pneumonia or pulmonary tuberculosis); 3. Pathological and histological confirmation of benign pulmonary nodule, malignant pulmonary nodule (including lung cancer), pneumonia, or pulmonary tuberculosis; 4. Voluntary provision of written informed consent and agreement to provide biological samples and clinical data.

Exclusion criteria

Exclusion criteria: 1. Age 80 years; 2. Presence of severe acute infection; 3. Presence of other systemic inflammatory diseases; 4. Pregnancy; 5. History of HIV infection; 6. History of primary immunodeficiency; 7. Diagnosis of lymphoma or other diseases similar to ANCA-associated vasculitis (AAV); 8. Severe psychiatric disorders, such as schizophrenia, depression, or bipolar disorder; 9. Inability to cooperate with sample collection or follow-up for any other reason.

Design outcomes

Primary

MeasureTime frame
Tumor markers;C-reactive protein;Routine blood test;Pulmonary function test;Coagulation function;Medication history;Biochemical indicators;Smoking history;Body mass index (BMI);Imaging examination (CT);Immune cells indicators;

Countries

China

Contacts

Public ContactChen Baofu

Taizhou Central Hospital (Taizhou University Hospital)

chenbf@tzc.edu.cn+86 137 0676 3092

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026