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A retrospective and observational study to construct a prediction model for liver metastasis and prognosis of AFP-positive gastric cancer using common clinical, imaging, and pathological data

A retrospective and observational study to construct a prediction model for liver metastasis and prognosis of alpha-fetoprotein-producing gastric cancer using common clinical, imaging, and pathological data

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500115549
Enrollment
Unknown
Registered
2025-12-29
Start date
2025-12-31
Completion date
Unknown
Last updated
2026-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Afp-positive gastric cancer

Interventions

Liver-metastasis group / Non-liver-metastasis group:None

Sponsors

The First Affiliated Hospital of Zhejiang University School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1.The results of gastroscopy or postoperative pathology confirmed it as gastric adenocarcinoma. 2. Before treatment, the patient's serum AFP was > (20ng/ml or the upper limit of normal), and/or postoperative pathological immunohistochemical AFP of the primary lesion of gastric tumor was + 3. There are no other serious comorbidities that affect survival, such as severe heart, brain and lung diseases, liver and kidney failure, etc. 4. There are no concurrent primary tumors 5. Have follow-up contact information and complete clinicopathological data

Exclusion criteria

Exclusion criteria: 1.Pathological types include differentiation patterns other than adenocarcinoma. 2.Coexistence of malignant tumors in other organs. 3.History of liver diseases such as acute or chronic hepatitis, cirrhosis, etc. 4.Significantly missing follow-up or clinicopathological data.

Design outcomes

Primary

MeasureTime frame
Predictive performance for liver metastasis and prognosis;

Countries

China

Contacts

Public ContactYongfeng Ding

The First Affiliated Hospital of Zhejiang University School of Medicine

dingyongfeng@zju.edu.cn+86 571 87235841

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026