Postoperative recovery quality
Conditions
Interventions
The non-opioid group:Anesthesia induction: dexmedetomidine 0.5µg/kg pumped within 10 minutes, esketamine 0.4mg/kg, propofol 2-2.5 mg/kg, cisatracurium 0.1-0.2mg/kg
Anesthesia maintenance: Esketamine at 0.25mg/kg/h was maintained until 30 minutes before the end of the surgery, dexmedetomidine at 0.1µg/kg/h was maintained until the end of the surgery, and propofol
Opioid Group:Anesthesia induction: Normal saline, sufentanil 0.4µg/kg, propofol 2-2.5mg/kg, cisatracurium 0.1-0.2mg/kg were pumped at the same volume and rate as dexmedetomidine. Anesthesia maintenanc
Sponsors
Yi Jishan Hospital,the First Affiliated Hospital of Wannan Medical College
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: (1) Shoulder arthroscopic surgery will be performed under elective general anesthesia; (2) Age 18-65 years old; (3)BMI is 18-30 kg/m^2; (4) American society of Anesthesiologists (ASA) Grade I-III; (5) Clearly understand the experimental process and voluntarily participate, signing the informed consent form.
Exclusion criteria
Exclusion criteria: (1)Patients who have been taking sedative and analgesic drugs for a long time due to pain; (2) Severe mental/cognitive impairment; (3) Severe heart, liver and kidney insufficiency, sick sinoatrial node syndrome, bradycardia (=180 mmHg or DBP>=100 mmHg); (7) Patients with hyperthyroidism; (8) Inability to communicate effectively or refusal to participate in research; (9)Patients who are allergic to or incompatible with any study drug and those participating in another intervention trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative recovery quality; | — |
Secondary
| Measure | Time frame |
|---|---|
| Hospital Anxiety and Depression Scale (HADS) score;NRS Pain score;The incidence of moderate to severe postoperative pain within 0-24 hours and 24-48 hours after the operation;The incidence of nausea and vomiting within 0-24 hours and 24-48 hours after the operation;The anesthesia recovery level of PACU, perioperative hemodynamics, and the occurrence frequency of hypertension and hypotension;Postoperative adverse reaction events; | — |
Countries
China
Contacts
Public ContactYa Cao;Borui Li
Yiji Mountain Hospital, the First Affiliated Hospital of Wannan Medical College
Outcome results
None listed