Thyroid diseases
Conditions
Interventions
No nerve block (Control):Patients in this group will receive standard general anesthesia alone, without any superficial cervical plexus block.
Ropivacaine, High-Volume High-Concentration:Patients will receive an ultrasound-guided bilateral superficial cervical plexus block with 20 mL of 0.375% ropivacaine per side, in addition to standard ge
Ropivacaine, High-Volume Low-Concentration:Patients will receive an ultrasound-guided bilateral superficial cervical plexus block with 20 mL of 0.25% ropivacaine per side, in addition to standard gene
Ropivacaine, Low-Volume High-Concentration:Patients will receive an ultrasound-guided bilateral superficial cervical plexus block with 10 mL of 0.375% ropivacaine per side, in addition to standard gen
Sponsors
The First Affiliated Hospital of Xinjiang Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18–65 years. 2. American Society of Anesthesiologists (ASA) physical status I–II. 3. Scheduled to undergo total thyroidectomy or lobectomy with isthmusectomy under general anesthesia. 4. Willing to participate in the study and having provided written informed consent.
Exclusion criteria
Exclusion criteria: 1. Allergy to ropivacaine or related anaesthetic drugs 2. Infection at the puncture site 3. Serious coagulation disorders. 4. Presence of uncontrolled severe cardiac, pulmonary, hepatic or renal diseases. 5. Pre-operative neurological deficit or cognitive impairment, MMSE score <=20, unable to cooperate with post-operative evaluation. 6. Inability to understand assessment scales such as QoR-15. 7. Pregnant or breastfeeding women. 8. Underwent surgery within the last 3 months; participated in another study within the last 30 days; 9. refuse to participate in this study. 10. ASA grade III or above
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Quality of Recovery-15 score at postoperative day 1; | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative pain intensity(Assessed using the Visual Analogue Scale);Total opioid consumption within 24 hours postoperatively;Time to first request for analgesia; Incidence and severity of postoperative nausea and vomiting;Complications related to superficial cervical plexus block; | — |
Countries
China
Contacts
Public ContactHai Guo
The First Affiliated Hospital of Xinjiang Medical University
Outcome results
None listed