Bronchus, lung, chest and other diseases
Conditions
Interventions
Regimen combination with propofol and sufentanil (PS group):High flow humidifying oxygen therapy (45L/min) + sedation program [Sufentanil 1g/kg, propofol 1-2mg/kg titrated to the target sedation depth
Regimen combination with midazolam and afentanil (MA group):High-flow humidified oxygen therapy (50L/min) + midazolam 0.045mg/kg, and 23mg/kg of afentanil were given at an interval of 1min. If the tar
Regimen combination with remimazolam and afentanil (RA group):High-flow moist oxygen therapy (50L/min) +Remimazolam 0.2mg/kg, and 23mg/kg of afentanil were given at an interval of 1min. If the target
Sponsors
Beilun District People's Hospital of Ningbo
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1.Age range 18-60 years 2.ASA grade I - III 3.No other serious systemic complications 4.Conscious and able to cooperate with examination 5.Patients gave informed consent and signed written informed consent
Exclusion criteria
Exclusion criteria: 1.Those who do not meet the inclusion criteria; 2.Patients with concurrent cardiovascular, liver and kidney, hematopoietic system, nervous system or systemic diseases; 3.Patients with a history of alcohol abuse or those who have been using opioids or sedatives for a long time; 4.Patients with severe cognitive impairment; 5.Patients with a history of asthma; 6.Pregnant and lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| VAS choke score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Perioperative hemodynamics;Hypoxia incidence;Patient resuscitation time;Patient satisfaction and Surgeon satisfaction;Postoperative adverse reactions;Postoperative sleep assessment; | — |
Countries
China
Contacts
Public ContactYunfei Cao
Beilun District People's Hospital of Ningbo
Outcome results
None listed