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The impact of stepwise enteral nutrition on gastrointestinal function and nutritional status in patients with severe stroke

The effects of stepwise enteral nutrition on gastrointestinal function and nutritional status in patients with severe stroke.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500115524
Enrollment
Unknown
Registered
2025-12-28
Start date
2026-01-01
Completion date
Unknown
Last updated
2026-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Severe stroke

Interventions

control group:Feeding method: Frequent feeding via nasogastric tube Estimate the total daily enteral nutrition solution volume at 25-30 kcal·kg-1·d-1. Divide this volume into four single doses and adm
experimental group:Feeding method: Three-lumen feeding tube step feeding. The Clinical Application Guidelines for Parenteral and Enteral Nutrition in Adult Patients in China (2023 Edition) state that

Sponsors

Beijing Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 100 Years

Inclusion criteria

Inclusion criteria: 1. Age >=18 years; 2. Meets the diagnostic criteria of the 2019 Chinese guidelines for the diagnosis of various major cerebrovascular diseases, and is confirmed by head CT or MRI to have acute stroke lesions; 3. Acute onset, admitted to the hospital within 24 hours of onset; 4. At the time of admission, the National Institutes of Health Stroke Scale (NIHSS) score is >=17 or the Glasgow Coma Scale (GCS) score is <=8.

Exclusion criteria

Exclusion criteria: 1. Patients with contraindications to enteral nutrition support therapy, such as intestinal obstruction, severe organic lesions of the digestive tract, or stress bleeding; 2. Patients with severe liver or kidney dysfunction, cachexia, or leukemia.

Design outcomes

Primary

MeasureTime frame
Compare the incidence of enteral nutrition intolerance in two groups of patients within 2 weeks after catheter placement and enteral nutrition.;The changes in the cross-sectional area of ??the gastric antrum were compared between the two groups of patients who received enteral nutrition after tube placement within 2 weeks.;

Secondary

MeasureTime frame
Compare the albumin, prealbumin, transferrin, and total protein levels in the two groups of patients at the time of catheter placement and two weeks after the start of enteral nutrition.;

Countries

China

Contacts

Public ContactSu Yin

Beijing Hospital

suyin3349@bjhmoh.cn+86 10 8513 6181

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026