Patients undergoing general anesthesia with fentanil-induced tracheal intubation
Conditions
Interventions
Group T (Tiglyldine Group):0.5 mg of tigelidine is prepared in 5 ml of solution iv.
Group S (Normal Saline Control Group):5 ml of 0.9% normal saline iv.
Sponsors
Weifang People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. ASA class I-III; 2. Aged 18-65 years; 3. Require the use of fentanil for endotracheal intubation under general anesthesia induction; 4. Voluntarily signed informed consent form.
Exclusion criteria
Exclusion criteria: 1. Drug allergy; 2. Sinus bradycardia; 3. Severe neurological, respiratory, or cardiovascular disease; 4. Anesthetic drug dependence; 5. Hepatic or renal dysfunction; 6. Gallbladder surgery; 7. Pregnancy, lactation, or delivery surgery; 8. Patients with upper respiratory tract infection within 2 weeks or other conditions that may induce spontaneous coughing.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of cough following fentanil injection; | — |
Secondary
| Measure | Time frame |
|---|---|
| Number of patients with coughs of different severity grades;Blood pressure;Heart rate;Pulse oxygen saturation;Other side effects associated with tiglyldine and fentanil; | — |
Countries
China
Contacts
Public ContactZhang Shaojie
Weifang People's Hospital
Outcome results
None listed