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Effect of Liposomal Bupivacaine Transversalis Fascia Plane Block versus Epidural Morphine on Postoperative Recovery Quality after Cesarean Delivery

Effect of Liposomal Bupivacaine Transversalis Fascia Plane Block versus Epidural Morphine on Postoperative Recovery Quality after Cesarean Delivery

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500115504
Enrollment
Unknown
Registered
2025-12-26
Start date
2025-12-30
Completion date
Unknown
Last updated
2026-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cesarean Section

Interventions

EM group:2.5 mg of morphine was administered via the epidural catheter during skin closure
LB-TFP group:After surgery, the parturient was placed in the supine position. The skin was disinfected and draped, and the ultrasound probe was covered with a disposable sterile protective sheath. A l
once the needle tip reached the space between the thoracolumbar fascia and the transversus fascia, the position was confirmed using the "hydrodissection technique." Aspiration revealed no blood, and 1
LB+EM group:At skin closure, 1.5 mg of morphine was administered through the epidural catheter, and the block was performed identically to the LB-TFP group after surgery.

Sponsors

Jinan Third People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 50 Years

Inclusion criteria

Inclusion criteria: 1. Age>=20 years? 2. Full-term pregnancy (gestational age between 37 and 42 weeks)? 3. ASA physical status classification of I or II? 4. Patients scheduled for cesarean section under neuraxial anesthesia?

Exclusion criteria

Exclusion criteria: 1. Refusal to sign the informed consent form 2. Relative contraindications to neuraxial anesthesia 3. Allergy to study drugs 4. Severe hepatic or renal insufficiency 5. History of severe psychiatric illness or other conditions preventing cooperation with assessment or trial 6. Inadequate intraoperative analgesia requiring rescue analgesia 7. Concurrent other surgeries 8. Number of previous cesarean sections >= 3 9. Pre-pregnancy body mass index > 45 kg/m^2

Design outcomes

Primary

MeasureTime frame
ObsQoR-11 scores postoperatively;The first time an interval of intravenous supplemental analgesia is required;Timing and frequency of diclofenac sodium administration postoperatively;First time to get out of bed successful;Time to first spontaneous voiding;Time to first passage of flatus;Incidence of adverse events (including somnolence, respiratory depression, nausea, vomiting, pruritus, urinary retention, hypotension, and puncture site hematoma);Patient satisfaction at 72 hours postoperatively;

Secondary

MeasureTime frame
Pain scores;Dosage of sufentanil administered at 24 hours postoperatively;

Countries

China

Contacts

Public ContactQin Wenwen

Jinan Third People's Hospital

1546205592@qq.com+86 85853684

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026