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A Study on Evaluating Hepatic Hemodynamics in Patients with Cirrhotic Portal Hypertension Based on 4D Flow MRI Technology

A Study on Evaluating Hepatic Hemodynamics in Patients with Cirrhotic Portal Hypertension Based on 4D Flow MRI Technology

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500115470
Enrollment
Unknown
Registered
2025-12-26
Start date
2025-12-31
Completion date
Unknown
Last updated
2026-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Liver Cirrhosis

Interventions

Cirrhosis patient group:None
Normal Control group:None

Sponsors

The Third Xiangya Hospital of Central South University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: (1) Patients with portal hypertension who have a confirmed etiology of liver cirrhosis (including HBV, HCV, cholestatic, and autoimmune hepatitis, etc.), and are older than 18 years of age. (2) For some patients who need to undergo transjugular intrahepatic portosystemic shunt (TIPS) surgery: no history of hepatic encephalopathy prior to TIPS surgery; the same type of Vitorr covered stent (Gore, USA) with consistent diameter is used during the TIPS procedure. (3) Complete clinical case data, with no loss of imaging data and follow-up related materials.

Exclusion criteria

Exclusion criteria: (1) Having contraindications to magnetic resonance imaging (MRI) examination. (2) Severe coagulation dysfunction and uncontrolled intrahepatic or systemic infection (3) Complicated with renal insufficiency. (4) Complicated with severe right heart failure as well as moderate to severe pulmonary hypertension. (4) Patients with other critical illnesses and those with incomplete medical record data collection. (5) For some patients who need to undergo transjugular intrahepatic portosystemic shunt (TIPS) surgery: A history of hepatic encephalopathy prior to TIPS surgery.

Design outcomes

Primary

MeasureTime frame
hepatic hemodynamics;Portal vein pressure;liver function;

Countries

China

Contacts

Public ContactLiang Qi

The Third Xiangya Hospital of Central South University

csuliangqi10@163.com+86 137 8731 8180

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026