FindTrial
Sign In

Study on the effect and mechanism of high-density transcranial direct current stimulation of the dorsolateral prefrontal cortex on the awakening of patients undergoing uterine malignant tumor surgery under general anesthesia with propofol

Study on the effect and mechanism of high-density transcranial direct current stimulation of the dorsolateral prefrontal cortex on the awakening of patients undergoing uterine malignant tumor surgery under general anesthesia with propofol

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500115460
Enrollment
Unknown
Registered
2025-12-26
Start date
2026-01-01
Completion date
Unknown
Last updated
2026-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Delayed awakening and disturbance of consciousness after general anesthesia with propofol

Interventions

sham HD-tDCS group:Sham high-density transcranial direct current stimulation
HD-tDCS group:high-density transcranial direct current stimulation

Sponsors

Xuzhou Central Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Voluntarily participate in the trial and sign the informed consent form; 2. Age 18-65 years old, ASA level I-II; 3. Elective uterine malignant tumor surgery under propofol general anesthesia.

Exclusion criteria

Exclusion criteria: 1. Refusal to sign the consent form; 2. History of neurological disease; 3. Skull or scalp injury or defect; 4. Having metal implants in the body; 5. Use of psychotropic medications within 2 weeks before surgery; 6. Propofol contraindications (such as egg, soy product allergy).

Design outcomes

Primary

MeasureTime frame
Eye opening time;—

Secondary

MeasureTime frame
Extubation time;PACU stay time;3-minute delirium diagnostic scale (3D-CAM);Numerical Scoring System (NRS);Riker Sedation-Agitation Score (SAS);Postoperative Quality of Recovery Scale (QoR);Montreal Cognitive Assessment (MoCA);Digit Symbol Substitution Test (DSST);—

Countries

China

Contacts

Public ContactZan Wang

Xuzhou Central Hospital

840547858@qq.com+86 17712986638

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026