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An evaluation study on the improvement of Diarrhea Symptoms and Changes in intestinal Flora by Probiotic Food (Bifidobacterium breve FPHC4024)

An evaluation study on the improvement of Diarrhea Symptoms and Changes in intestinal Flora by Probiotic Food (Bifidobacterium breve FPHC4024)

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500115445
Enrollment
Unknown
Registered
2025-12-26
Start date
2025-12-31
Completion date
Unknown
Last updated
2026-01-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gastroenteritis, diarrhea

Interventions

Control group:None
Observation group:None

Sponsors

Shantou Chenghai District People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: (1)The clinical diagnosis is gastroenteritis. (2) There are clinical symptoms of varying degrees such as vomiting, diarrhea and abdominal pain. (3) The shape of the stool changes, presenting as loose, watery, mucous or bloody stool. (4) The frequency of bowel movements has increased compared to usual. (5) No dehydration or poisoning symptoms, and the general condition is good. (6) Voluntarily participated in the trial and signed the informed consent form for the trial research. (7) The experimental group took Bifidobacterium brevis FPHC4024 probiotics (food) for >=7 days, while the control group did not take any probiotics.

Exclusion criteria

Exclusion criteria: (1) Surgical history; (2) Digestive system malformations; (3) Gene therapy within the last 6 months. (4) Pregnant or lactating women or those with plans to conceive within 3 months; (5) Those who did not consume the test sample, or whose data is incomplete and affects the judgment of efficacy or safety. (6)Concurrent use of other probiotics, antibiotics, immunosuppressants, or other drugs or foods that may interfere with the results.

Design outcomes

Primary

MeasureTime frame
Compare the intervention effects between groups;The distribution of probiotics in feces, especially the abundance of newly colonized probiotics and Enterococcus faecalis.;Subjective feelings of consumption;

Secondary

MeasureTime frame
During the follow-up, the fecal properties and defecation frequency of the patients were observed.;

Countries

China

Contacts

Public ContactHan Hui

Shantou Chenghai District People's Hospital

hanhui2023@126.com+86 137 2767 7953

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026