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Study on the Antihypertensive Efficacy of Repetitive Transcranial Magnetic Stimulation in Individuals with Prehypertension

Study on the Antihypertensive Efficacy of Repetitive Transcranial Magnetic Stimulation in Individuals with Prehypertension

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500115434
Enrollment
Unknown
Registered
2025-12-26
Start date
2025-12-29
Completion date
Unknown
Last updated
2026-02-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypertension

Interventions

Experimental group:Experimental group – real rTMS protocol: The left dorsolateral prefrontal cortex (DLPFC) was localized as the target stimulation site using the conventional "5-cm rule." Participa
Control group:Control group: Participants received sham rTMS by rotating the coil 90° so that it was perpendicular to the scalp
all other stimulation parameters were identical to those used for real stimulation.

Sponsors

The First Affiliated Hospital of Chongqing Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 55 Years

Inclusion criteria

Inclusion criteria: (1) Aged 18–55 years, right-handed. (2) Screening blood pressure within the pre-hypertensive range. (3) Willing to receive rTMS intervention.

Exclusion criteria

Exclusion criteria: (1) Presence of any metallic implants (2) Previous use of antihypertensive medication (3) Major systemic illness or current use of any drugs/supplements that affect blood pressure (4) Cognitive impairment or any condition precluding compliance with treatment, follow-up, or questionnaire assessment (5) High cardiovascular risk profile for hypertension (6) Pregnancy

Design outcomes

Primary

MeasureTime frame
Blood pressure;

Secondary

MeasureTime frame
PHQ-9 depression Screening scale;GAD-7 anxiety scale;Composite Autonomic Symptom Score 31;PSS Stress Perception Scale;PSQI Pittsburgh sleep Quality Scale;

Countries

China

Contacts

Public ContactLv Furong

The First Affiliated Hospital of Chongqing Medical University

2658323899@qq.com+86 139 0836 5685

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 15, 2026