The crown of the impacted tooth was closely adjacent to the root of the neighboring tooth, resulting in external root resorption of the adjacent tooth.
Conditions
Interventions
Study group:Implant CGF
Control group:none
Sponsors
Hospital of Stomatology Wuhan University
Eligibility
Sex/Gender
All
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: 1. Male or female participants aged 18 to 45 years. 2. Patients who meet the indications for extraction of an impacted tooth. 3. Cone-beam computed tomography (CBCT) demonstrates a localized area of external root resorption on the distal surface or apex of the adjacent tooth root, closely contacting the crown of the impacted tooth. Assessment method: All cases are independently evaluated by two experienced oral radiologists. In case of disagreement, the diagnosis will be determined by a third senior radiologist. 4. Patients with no other identifiable causes of external root resorption, such as orthodontic treatment, trauma, tumor, or cyst. 5. The tooth affected by external root resorption is a fully erupted permanent tooth, with no pulp or periodontal pathology, and demonstrates normal pulp vitality on electric pulp testing. 6. No contraindications to tooth extraction. 7. The participant has voluntarily signed the informed consent form and agrees to participate in the study and comply with the study protocol.
Exclusion criteria
Exclusion criteria: 1. Presence of severe systemic disease rendering the patient unable to tolerate oral surgery. 2. Pregnant or planning to become pregnant in the near future. 3. The tooth affected by external root resorption shows obvious coronal or periodontal pathology. 4. Diagnosis of radiation-induced or medication-related osteomyelitis of the jaw. 5. Current or prior use of medications known to affect bone or periodontal healing (e.g., long-term corticosteroids or antiresorptive agents). 6. Patients with psychiatric disorders or cognitive impairment that may affect compliance. 7. Patients currently undergoing orthodontic treatment. 8. Participation in another clinical trial within the past one month. 9. Any other condition deemed unsuitable for inclusion by the investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Measurement of the length and width of the affected adjacent tooth root;Regeneration score of the external root resorption area of the adjacent tooth; | — |
Secondary
| Measure | Time frame |
|---|---|
| Volume change rate (?V) of the external root resorption area;Electric pulp test (EPT) results of the affected adjacent tooth;Periodontal status of the affected adjacent tooth; | — |
Countries
China
Contacts
Public ContactZhao Jihong
Hospital of Stomatology Wuhan University
Outcome results
None listed