Tumor
Conditions
Interventions
A1:1. Alcohol group: Use 75% medical alcohol for skin disinfection, following standard PICC catheter maintenance procedures. The disinfection area should be centered on the puncture site and have a di
A2:1. Chlorhexidine group: Skin disinfection was performed using a 0.5% chlorhexidine ethanol solution, following the same procedure as the alcohol group.
2. Iodine group: Skin disinfection was perfor
A3:1. Iodine group: Use 0.5% iodine solution for skin disinfection, following the same procedure as the alcohol group.
2. Alcohol group: Use 75% medical alcohol for skin disinfection, following standa
Sponsors
Peking Union Medical College Hospital, Chinese Academy of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Cancer patients scheduled for chemotherapy who have undergone ultrasound-guided PICC placement; 2. Able to maintain the catheter regularly at the selected center; 3. Age between 18 and 75 years; 4. No time or place disorientation; 5. Signed informed consent form.
Exclusion criteria
Exclusion criteria: 1. The patient has clear evidence of infection before catheter placement; 2. The patient has obvious skin damage or local skin disease at the catheter placement site; 3. The patient has significant coagulation dysfunction (coagulation dysfunction includes the following ranges: platelets <100x10^9, prothrombin time <10.4s, activated partial thromboplastin time <22.7s, fibrinogen <1.8/L, thrombin time <14s); 4. The patient is allergic to alcohol, povidone-iodine, or chlorhexidine; 5. The patient is currently using medications that may affect skin reactions (such as corticosteroids); 6. Pregnant or lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| CASI incidence; | — |
Secondary
| Measure | Time frame |
|---|---|
| Types and extent of CASI;Catheter-related complications;Maintenance operation time; | — |
Countries
China
Contacts
Public ContactSun Wenyan
Peking Union Medical College Hospital, Chinese Academy of Medical Sciences
Outcome results
None listed