Dentin hypersensitivity
Conditions
Interventions
Experimental group:Use the experimental toothpaste every morning and evening, brushing for 2 minutes each time.
Positive control:Use the positive control toothpaste every morning and evening, brushing for 2 minutes each time.
Negative control:Use the negative control toothpaste every morning and evening, brushing for 2 minutes each time.
Sponsors
School & Hospital of Stomatology Wuhan University
Eligibility
Sex/Gender
All
Age
20 Years to 55 Years
Inclusion criteria
Inclusion criteria: 1. Age between 20 and 55 years old; 2. Good overall health; 3. Symptoms of tooth sensitivity, with at least two teeth (the two sensitive teeth should be in different quadrants and not adjacent) having exposed root dentin. When tested using the Schiff cold air method, at least two teeth must score greater than or equal to 2, with a VAS score greater than or equal to 4, and the tooth sensitivity threshold must be below 20 grams when tested using the Yeaple probe. 4. Must have a daily brushing habit (twice a day, morning and evening).
Exclusion criteria
Exclusion criteria: 1. History of severe oral disease, chronic illness, or allergy to the test product; 2. Progressive periodontal disease or periodontal treatment (including periodontal surgery) within the past year; 3. Mobility of sensitive teeth greater than 1; 4. Extensive dental restorations, suspected pulpitis, caries, enamel cracks, or abutment teeth for removable partial dentures; 5. Taking or currently taking the following medications within one month prior to participation in the study: anticonvulsants, antihistamines, antidepressants, sedatives, tranquilizers, anti-inflammatory agents, and analgesics; 6. Patients with intermittent pain (e.g., lower back pain, arthritis); 7. Participation in a desensitizing toothpaste study within the past 3 months or daily use of other desensitizing toothpastes; 8. Currently participating in other clinical trials; 9. History of allergy to personal care products or toothpaste ingredients; 10. Pregnant or lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Schiff index; | — |
Secondary
| Measure | Time frame |
|---|---|
| Yeaple index; | — |
Countries
China
Contacts
Public ContactBaojun Tai
School & Hospital of Stomatology Wuhan University
Outcome results
None listed