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Research on the Influence and Mechanism of Probiotics on Peristomal Dermatitis in Patients

Research on the Influence and Mechanism of Probiotics on Peristomal Dermatitis in Patients

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500115398
Enrollment
Unknown
Registered
2025-12-25
Start date
2026-01-01
Completion date
Unknown
Last updated
2026-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

wound

Interventions

Experimental group:On top of routine care, apply a lactobacillus solution to the stoma dermatitis area, leave it for 15 minutes, and wait for it to be absorbed and dry.
Control group:As part of routine care, use saline to clean the inflamed area around the stoma.

Sponsors

Trauma Center of West China Hospital, Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Patients with bladder cancer who have a urinary stoma for follow-up or re-examination; 2. Patients with peristomal skin inflammation (diagnosed by a doctor); 3. Voluntarily participating in this study and signing the informed consent form; 4. Have not used probiotics, prebiotics, or postbiotics before enrollment.

Exclusion criteria

Exclusion criteria: 1. Individuals who, in addition to bladder cancer, also have other diseases of the intestines or urinary system; 2. Individuals with mental illnesses; 3. Individuals participating in other clinical trials at the same time.

Design outcomes

Primary

MeasureTime frame
The bacterial community structure and abundance of the skin around the urinary tract stoma;

Secondary

MeasureTime frame
Levels of inflammatory factors in peripheral blood;Incidence and onset time of peristomal dermatitis;The effective replacement rate of ostomy bags;Observing the patient's recovery status includes the healing grade, healing rate, and healing time of peristomal dermatitis.;Pain assessment (measured using Visual Analog Scale [VAS], complication Clavien-Dindo classification, length of hospital stay, number of readmissions within one month, etc.);

Countries

China

Contacts

Public ContactChangqing Liu

Trauma Center of West China Hospital, Sichuan University

lcq2084@163.com+86 189 8060 8591

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026