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Study on the Effect of Cortical Bone Decortication on Guided Bone Regeneration in the Posterior Mandible

Study on the Effect of Cortical Bone Decortication on Guided Bone Regeneration in the Posterior Mandible

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500115391
Enrollment
Unknown
Registered
2025-12-25
Start date
2026-01-01
Completion date
Unknown
Last updated
2026-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Peri-implant bone defect

Interventions

Decortication group:None
Non-decortication group:None

Sponsors

West China Hospital of Stomatology, Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Implant placement performed in the posterior region at least 3 months after tooth extraction; 2. Presence of a buccal bone defect following implant placement, with the defect extent involving less than 50% of the implant length (classified as a Class 1/4 defect according to Terheyden’s classification) (Cordaro et al., 2019); 3. Patients who are systemically healthy or have stable systemic conditions and are able to tolerate routine oral implant surgery; 4. Patients enrolled between July 2020 and July 2023; 5. Age >= 18 years.

Exclusion criteria

Exclusion criteria: 1. Severe systemic diseases (e.g., uncontrolled diabetes mellitus, immunodeficiency, etc.) 2. Long-term use of medications that may affect bone metabolism or healing (e.g., corticosteroids) 3. Heavy smoking (>10–20 cigarettes/day) or chronic alcohol abuse 4. Poor oral hygiene or uncontrolled periodontitis 5. Pregnancy or a history of head and neck radiotherapy

Design outcomes

Primary

MeasureTime frame
Change in horizontal hard tissue thickness (HT0 to HT1);Change in bucco-lingual dimension (BLD0 and BLD1);

Secondary

MeasureTime frame
marginal bone loss;Soft tissue health;Implant survival rate;

Countries

China

Contacts

Public ContactXiong Yi

West China Hospital of Stomatology, Sichuan University

xiongraise@163.com+86 181 4018 9201

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026