schizophrenia
Conditions
Interventions
Control group:NA
schizophrenia group:NA
Sponsors
Affiliated Kangning Hospital of Ningbo University
Eligibility
Sex/Gender
All
Age
13 Years to 17 Years
Inclusion criteria
Inclusion criteria: Patient Group: 1. Aged between 13 and 17 years; 2. Met the diagnostic criteria for schizophrenia as defined by the DSM-5, with confirmation through the Kiddie Schedule for Affective Disorders and Schizophrenia - Present and Lifetime Version (K-SADS-PL) interview; 3. First episode and antipsychotic-naive 4. Right-handed; 5. Normal uncorrected or corrected vision; 6. Attained at least a primary school education, demonstrated roughly normal intellectual function, and were capable of comprehending the informed consent form and the research content. Control Group: 1. Aged 13-17 years, matched 1:1 with the patient group based on age and sex; 2. Clinically excluded for autism spectrum disorders and confirmed by the K-SADS-PL interview to have no current or past psychiatric disorders; 3. No family history of psychiatric disorders within three generations of both paternal and maternal lineages; 4. Right-handed; 5. Normal uncorrected or corrected vision; 6. Attained at least a primary school education, demonstrated roughly normal intellectual function, and capable of comprehending the informed consent form and research content.
Exclusion criteria
Exclusion criteria: Patient Group: 1. Presence of severe physical illnesses, history of traumatic brain injury, or history of epileptic seizures; 2. Comorbid psychiatric disorders identified by the K-SADS-PL interview, such as intellectual disability, bipolar disorder, or major depressive disorder; 3. Clinical features suggestive of autism spectrum disorders; 4. History of electroconvulsive therapy within the past 6 months; 5. High imminent risk of impulsive aggression or self-harm; 6. Any other conditions that would compromise the ability to complete the study procedures. Control Group: 1. Presence of severe physical illnesses, history of traumatic brain injury, or history of epileptic seizures; 2. Any other conditions that would prevent completion of the test procedures.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| severity of symptoms; | — |
Secondary
| Measure | Time frame |
|---|---|
| EEG;Heart rate variability, HRV; | — |
Countries
China
Contacts
Public ContactXingyue Jin
Affiliated Kangning Hospital of Ningbo University
Outcome results
None listed