Skip to content

Efficacy Observation of Modified Uvulopalatopharyngoplasty in the Treatment of Obstructive Sleep Apnea Complicated with Depressive Disorder

Efficacy Observation of Modified Uvulopalatopharyngoplasty in the Treatment of Obstructive Sleep Apnea Complicated with Depressive Disorder

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500115368
Enrollment
Unknown
Registered
2025-12-25
Start date
2026-01-01
Completion date
Unknown
Last updated
2026-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

obstructive sleep apnea and depression

Interventions

Control Group:Patients in the experimental group underwent H-UPPP surgery under general anesthesia.
Control Group:Routine conservative treatments, including weight control, smoking and alcohol cessation, and sleeping in the lateral position at night.

Sponsors

The Affiliated Dazu's Hospital of Chongqing Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Aged >= 18 years old and 30 events/h). 3. With a confirmed diagnosis of depressive disorder. 4. The experimental group met the surgical indications for H-UPPP, which was predicted by using the Friedman classification or TCM surgical efficacy scoring prediction system. 5. Written informed consent was obtained from the patients and their family members.

Exclusion criteria

Exclusion criteria: 1. Complicated with stroke, Alzheimer’s syndrome, and other diseases that may cause cognitive decline or central nervous system diseases. 2. Complicated with other sleep disorders other than obstructive sleep apnea . 3. A history of alcoholism or illicit drug abuse. 4. Patients with severe depressive disorder. 5. Patients with functional diseases of vital organs.

Design outcomes

Primary

MeasureTime frame
Sleep structure;

Secondary

MeasureTime frame
Hamilton Anxiety Rating Scale;Montgomery and Asberg Depression RatingScale;Zung Self-rating Depression Scale;Patients’Health Questionnaire Depression Scale-9 item;

Countries

China

Contacts

Public ContactGang Lin

The Affiliated Dazu's Hospital of Chongqing Medical University

543287875@qq.com+86 138 8375 2004

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026