Apparent treatment-resistant hypertension
Conditions
Interventions
Control group:None
Exposed Group:None
Sponsors
Peking Union Medical College Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1.Adult male or female patients aged >=18 years and <=70 years; 2.Diagnosed with apparent resistant hypertension and type 2 diabetes; 3.Having visited the outpatient clinic of Peking Union Medical College Hospital at least three times with complete office blood pressure records, with the interval between the first outpatient visit and the most recent outpatient visit being no less than six months;
Exclusion criteria
Exclusion criteria: 1.Presence of any serious comorbidity that limits life expectancy, such as malignancy; 2.Presence of a cause of secondary hypertension (e.g., renal artery stenosis, uncontrolled or untreated hyperthyroidism, uncontrolled or untreated hypothyroidism, hyperparathyroidism, pheochromocytoma, Cushing's syndrome, or coarctation of the aorta). Obstructive sleep apnea is not included. 3.Severe renal insufficiency (eGFR 40 kg/m^2); 5.Pregnancy, breastfeeding, or planning pregnancy; 6.Type 1 diabetes; 7.Adverse cardiovascular and renal events within 3 months before the study; 8.Poor medication compliance;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| major adverse cardiovascular and renal events; | — |
Secondary
| Measure | Time frame |
|---|---|
| Renal event;Changes in systolic blood pressure;The achievement rate of target diastolic blood pressure;The achievement rate of target systolic blood pressure;NYHA Functional Classification;Changes in diastolic blood pressure;Cardiovascular death;All cause mortality;Heart failure;hypertension-mediated organ damage;Stroke;Nonfatal myocardial infarction;Coronary Heart Disease; | — |
Countries
China
Contacts
Public ContactXiaowei Yan
Peking Union Medical College Hospital
Outcome results
None listed