Skip to content

A retrospective cohort study on the clinical application of metagenomic next-generation sequencing technology in patients with invasive pulmonary aspergillosis

A retrospective cohort study on the clinical application of metagenomic next-generation sequencing technology in patients with invasive pulmonary aspergillosis

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500115361
Enrollment
Unknown
Registered
2025-12-25
Start date
2026-01-01
Completion date
Unknown
Last updated
2026-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Invasive pulmonary aspergillosis

Interventions

Observation Group of Invasive Pulmonary Aspergillosis:None

Sponsors

Quzhou People Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Age >=18 years old; 2. Simultaneously undergo mNGS testing and traditional etiological testing; 3. Have test results for other pathogens, including but not limited to fungal cultures, acid-resistant staining and PCR tests for Pneumocystis jirovecii, Mycobacterium tuberculosis and cytomegalovirus. 4. Clinically diagnosed IPA

Exclusion criteria

Exclusion criteria: 1. Incomplete clinical data; 2. CMTs and mNGS tests were not conducted simultaneously; 3. Under the age of 18;

Design outcomes

Secondary

MeasureTime frame
ICU mortality rate and 28-day mortality rate;

Primary

MeasureTime frame
The diagnostic value of mNGS and CMTs for IPA;

Countries

China

Contacts

Public ContactFang Honglong

Quzhou People Hospital

13022646672@dingtalk.com+86 570 312 5041

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026