Postoperative pain in patients undergoing gynecological laparoscopic surgery
Conditions
Interventions
Buccal Acupuncture Group:In addition to standard general anesthesia, patients receive standardized buccal acupuncture intervention after anesthesia induction. This involves needle insertion at 16 spec
Control Group:Patients receive the identical standard general anesthesia protocol as the Buccal Acupuncture Group. SPI monitoring is employed throughout the procedure (target range: 20-50) to precisel
Sponsors
Dalian Women and Children’s Medical Center (Group)
Eligibility
Sex/Gender
Female
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Gender and age: female patients between 18 and 65 years old; 2. Physical condition: ASA grade I or II (i.e. physical condition good or suffering from mild systemic diseases, but functional compensation is sound); 3. Body mass index (BMI): ranging from 22 kg/m ^2 to 28 kg/m^2; 4. Informed consent: fully understand the content of this study, voluntarily participate in and sign the written informed consent.
Exclusion criteria
Exclusion criteria: 1.Major organ dysfunction: Patients with severe heart, lung, liver, kidney and other important organ organic diseases, or functional decompensation; 2.Infection and coagulation disorders: Patients with clear signs of infection or coagulation disorders were found by preoperative laboratory examination (blood routine, coagulation function, etc.); 3. Malignant tumor: a patient with a definite pathological diagnosis of malignant tumor; 4. Contraindications of buccal acupuncture: Patients with local facial infection, damage, bleeding tendency, acupuncture syncope history and other contraindications of buccal acupuncture treatment, or extremely afraid of acupuncture and unable to receive. 5. Drugs and mental status: long term regular use of analgesic and sedative drugs (such as opioids, non steroidal anti-inflammatory drugs, anti anxiety drugs, etc.); Or suffering from mental illness or cognitive impairment and unable to cooperate in completing the study evaluation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 24-hour postoperative rescue-analgesic rate;Time to first postoperative pain sensation.;Total intraoperative consumption of remifentanil.; | — |
Secondary
| Measure | Time frame |
|---|---|
| Serum levels of pain mediators, inflammatory factors, and stress indicators (including Substance P, Prostaglandin E2, Interleukin-6, Tumor Necrosis Factor-a, Cortisol, and Norepinephrine).;Intraoperative hemodynamic parameters (MAP, HR).;Incidence of postoperative nausea and vomiting (PONV) and shoulder discomfort.; | — |
Countries
China
Contacts
Public ContactQi Pan
Dalian Women and Children’s Medical Center (Group)
Outcome results
None listed