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Analysis of the efficacy of targeted therapy or immunotherapy in patients with lung cancer complicated with diabetes: A multicenter retrospective study

Analysis of the efficacy of targeted therapy or immunotherapy in patients with lung cancer complicated with diabetes: A multicenter retrospective study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500115324
Enrollment
Unknown
Registered
2025-12-24
Start date
2025-12-24
Completion date
Unknown
Last updated
2026-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lung cancer

Interventions

Observation group:N/A

Sponsors

The Army Characteristic Medical Center of the People's Liberation Army of China
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.Age >= 18 years old; 2.Previously pathologically confirmed lung cancer (both non-small cell lung cancer and small cell lung cancer can be included); 3.At the same time, it was concurrently diagnosed as type 2 diabetes mellitus (T2DM), and there was a record of standardized hypoglycemic treatment during or before tumor treatment; 4.Have received at least one targeted therapy (such as EGFR-TKI, ALK-TKI, etc.) or immunotherapy (ICI) for at least two cycles, and have complete treatment/follow-up data (with at least one efficacy evaluation); 5.Sufficient clinical data can be used to evaluate hypoglycemic regimens, tumor treatment regimens, and therapeutic outcomes.

Exclusion criteria

Exclusion criteria: 1.The hypoglycemic treatment plan is not clear, the treatment records are incomplete or there is a lack of follow-up data; 2.Previously participated in interventional clinical trials and the treatment plan was significantly different from the conventional treatment; 3.Before tumor treatment, the patient's blood glucose or hypoglycemic treatment was severely unstable or fluctuated frequently, making it difficult to define the "exposure" period.

Design outcomes

Primary

MeasureTime frame
Clinical efficacy;

Countries

China

Contacts

Public ContactLi Li

The Army Characteristic Medical Center of the People's Liberation Army of China

lili10119@126.com+86 139 8303 5673

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026