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The Impact of Tissue Perfusion Pressure on Postoperative Acute Kidney Injury in Off-Pump Coronary Artery Bypass Grafting: A Prospective, Cohort Study

The Impact of Tissue Perfusion Pressure on Postoperative Acute Kidney Injury in Off-Pump Coronary Artery Bypass Grafting: A Prospective, Cohort Study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500115294
Enrollment
Unknown
Registered
2025-12-24
Start date
2025-12-30
Completion date
Unknown
Last updated
2026-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute kidney injury

Interventions

TPP=34mmhg group:none

Sponsors

The Affiliated Hospital of Qingdao University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Patients scheduled for off-pump coronary artery bypass grafting; 2. Age >= 18 years; 3. American Society of Anesthesiologists (ASA) physical status classification of I-IV; 4. Has provided signed informed consent.

Exclusion criteria

Exclusion criteria: 1. Presence of other major comorbidities: severe infection (e.g., sepsis) or terminal malignancy (life expectancy < 1 year); myocardial infarction, stroke, or major trauma occurring within 3 months prior to surgery. 2. History of mental illness or long-term use of psychiatric medications. 3. Emergency surgery.

Design outcomes

Primary

MeasureTime frame
Acute kidney injury;—

Secondary

MeasureTime frame
Acute liver injury;severe ischemic early liver injury;Myocardial injury;Postoperative pulmonary infection;Postoperative wound infection;Mediastinitis;Endocarditis;stroke;30-day postoperative mortality;—

Countries

China

Contacts

Public ContactWei Feng

The Affiliated Hospital of Qingdao University

youzhuang_zhu@qdu.edu.cn+86 532 8291 9395

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026