Hip Fracture
Conditions
Interventions
PENG Group: All subjects in the PENG Group will receive a PENG block + LFCN block.Preparation: 133mg liposomal bupivacaine (10ml) + 0.75% bupivacaine (10ml) + normal saline (5ml), total volume 25ml. U
LIA Group:Subjects in the LIA group will receive an ultrasound scan in the same area prior to general anesthesia, but do not receive a PENG block + LFCN block. The orthopedic surgeons perform local in
Sponsors
Shanghai Fengxian Disrict Central Hospital
Eligibility
Sex/Gender
All
Age
55 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1.Patients scheduled for primary unilateral total hip arthroplasty; 2.Age 55–85 years; 3.Body Mass Index (BMI): 18–30 kg/m^2; 4.ASA Physical Status Classification I–III; 5.Voluntary participation in this study and provision of signed informed consent.
Exclusion criteria
Exclusion criteria: 1.Inability to cooperate; 2.Contraindications to regional nerve blocks or local infiltration analgesia; 3.Allergy to any component of the study drugs; 4.Chronic pain or opioid dependence; 5.Severe hepatic or renal insufficiency.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Resting and activity Visual Analogue Scale (VAS) scores at postoperative hour 1, 6,12,24,48, 72h; | — |
Secondary
| Measure | Time frame |
|---|---|
| Intraoperative remifentanil consumption;Intraoperative hemodynamic changes;Time to first rescue analgesia and rescue analgesia rate within 72 hours postoperatively;The use of patient-controlled analgesia pump;Time to first ambulation and ambulation rate within 72 hours postoperatively;Lower limb muscle strength changes ;Hip flexion range of motion.;Incidence of adverse events;Patient satisfaction;Time to hospital discharge; | — |
Countries
China
Contacts
Public ContactLiu Rong
Shanghai Fengxian Disrict Central Hospital
Outcome results
None listed