Skip to content

Heart-Brain Connection: Long-term Study on Cardiac Nerve Function and Cognitive Changes in Elderly Diabetic Patients

A Prospective Cohort Study on Cardiac Autonomic Nerve Function and Cognitive Impairment in Elderly Diabetic Patients

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500115276
Enrollment
Unknown
Registered
2025-12-24
Start date
2025-12-30
Completion date
Unknown
Last updated
2026-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cognitive impairment in elderly diabetic patients

Interventions

Sponsors

Shenzhen Center for Disease Control and Prevention
Lead Sponsor

Eligibility

Sex/Gender
All
Age
50 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. The date of birth range is from January 1, 1955 to December 31, 1975, which means the age at enrollment is 50-70 years old. 2. Meet the diagnostic criteria for diabetes mellitus; 3. Permanent residents of Shenzhen City.

Exclusion criteria

Exclusion criteria: 1. Situations where it is inappropriate to perform Cardiac Autonomic Reflex Tests (CARTs); 2. Abnormal MMSE or MocA-B outcome; 3. Severe hepatic and renal failure, history of hospitalization for ASCVD or heart failure within the past 3 months, history of malignant tumors that seriously affect life expectancy, other critical illnesses, severe mental illnesses, or physical disabilities. 4. Other reasons or researchers consider that they cannot participate in the study.

Design outcomes

Primary

MeasureTime frame
Cognitive function abnormalities;

Secondary

MeasureTime frame
Other diabetic complications;The state of cardiac autonomic nerve function;Changes in cognitive function scores;

Countries

China

Contacts

Public ContactChen Xiao

Shenzhen Center for Disease Control and Prevention

chenxiao@szcdc.net+86 755 2561 3578

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026