Pain after lumbar surgery
Conditions
Interventions
Exposure group:None
Sponsors
Hospital of Chengdu University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1.Subjects can understand the procedures and methods of this clinical trial (including pain intensity assessment methods), and after full informed consent, they voluntarily participate, and the informed consent form is signed by the subjects themselves or legal guardians. 2.Patients who need single-level or multi-level lumbar decompression or (and) decompression and fusion due to illness. 3.Subjects were classified as I-III according to the classification standard of American Society of Anesthesiologists (ASA). 4.When signing the informed consent form, the person is 18<=age <=80 years old, regardless of gender. 5.Female or male subjects of childbearing age must agree to take effective contraceptive measures by themselves and their partners within 30 days after signing the informed consent.
Exclusion criteria
Exclusion criteria: 1.Those who are allergic to amide local anesthetics (such as lidocaine, bupivacaine, tetracaine and ropivacaine, etc.), opioid drugs or any components of drugs used in this experiment, or have a history of idiopathic reactions, or those who are allergic (such as allergic to two or more drugs, food or pollen). 2.Physical conditions (such as rheumatoid arthritis, chronic neuropathic pain, etc.) unrelated to single-level or multi-level lumbar decompression or decompression and fusion may confuse postoperative pain assessors. 3.Coagulation dysfunction (platelet < 50× 10^9/L), patients with high bleeding risk, severe liver dysfunction (Child-Pugh C grade), severe renal dysfunction (receiving dialysis treatment before operation) and severe cardiovascular dysfunction. 4.Pregnant and lactating women who are currently breastfeeding or who have not been artificially breastfed but are less than 6 months after delivery. 5.The researcher thinks that it will be impossible to evaluate the curative effect or impossible to complete the expected course of treatment and follow-up, which is not suitable for participating in this trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Consumption of opioid analgesics; | — |
Secondary
| Measure | Time frame |
|---|---|
| Adverse event;Overall satisfaction score of subjects with analgesia;Vital signs;Numerical rating scale;Electrocardiogram;Postoperative hospitalization time;Laboratory examination;Time of first receipt of remedial analgesic medication;Overall satisfaction score of researchers on analgesia;Consumption of non-opioid analgesic drugs; | — |
Countries
China
Contacts
Public ContactYu Yang
Affiliated Hospital of Chengdu University of Traditional Chinese Medicine
Outcome results
None listed