Hypoxemia
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Age >=18 years old; 2. Gender is not limited; 3. Body mass Index (BMI) : 18.5-30kg/m ²; 4.ASA is classified into grades I to III; 5. Endoscopic ultrasound examination of the upper digestive tract (esophagus, stomach); 6. Be able to understand the plan and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Patients with difficult airways; 2. Patients with high-risk factors such as reflux and aspiration; 3. History of upper gastrointestinal surgery; 4. Previous lung surgeries, pneumothorax, pulmonary tuberculosis, and pleural effusion; 5. Have respiratory diseases (chronic obstructive pulmonary disease, respiratory tract infections, pulmonary infections, asthma, emphysema, etc.); 6. Patients with severe liver or kidney dysfunction; 7. Patients with anemia; 8. Pregnant patients; 9. History of mental illness;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of hypoxemia during the examination (SpO2 10 seconds); | — |
Secondary
| Measure | Time frame |
|---|---|
| The occurrence of body movement response (involuntary limb or body movement in patients during endoscopic ultrasound examination) during the examination;Degree of choking cough during the examination (Grade I: No choking cough, even breathing; Grade II: Single mild choking cough; Grade III: multiple choking coughs, but lasting less than 15 seconds; Grade IV: Continuous choking cough, lasting more than 15 seconds);The incidence of severe hypoxemia (SpO2 10 seconds);The lowest blood oxygen saturation during the examination and recovery period;Dosage of propofol;Duration of recovery;Respiratory comfort in the anesthesia recovery room (scored using a numerical assessment scale, with a score range from 0 to 10, and the higher the score, the more comfortable it is);The duration of stay in the anesthesia recovery room;The use of vasoactive drugs (atropine, ephedrine) during the examination period;Record HR, MAP and SpO2 before anesthesia induction (T0), when the endoscope passes through the throat (T1), at the beginning of endoscopy (T2), at the end of endoscopy (T3), when the patient wakes up (T4), and when leaving the anesthesia recovery room (T5);Record the satisfaction scores of patients (after regaining consciousness), anesthesiologists, recovery room nurses and digestive endoscopists;Record the occurrence of adverse reactions such as nausea, vomiting and laryngeal spasm in patients; | — |
Countries
China
Contacts
General Hospital of Ningxia Medical University