Cardiac Resynchronization
Conditions
Interventions
Patients with heart failure complicated with LBBB to be treated by CRT:None
LBBB patients with LVEF reservation:None
LVEF reduction in non-LBBB patients:None
Healthy control group:None
Sponsors
The First Hospital of China Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Healthy adults 1) Age >=18 years old; 2) Normal blood pressure (139-90/89-60 MMHG); 3) Body mass Index (BMI) =150ms; LBBB;" The best drug treatment should be at least three months before implantation 2) Age: 18-79 years old 3. LBBB patients with LVEF preservation: LVEF>=53%; LBBB 2) Age: 18-79 years old 4. Non-lbbb patients with reduced LVEF: 1) LVEF<=35%, not LBBB 2) Age: 18-79 years old
Exclusion criteria
Exclusion criteria: 1. Healthy adults 1) Suffering from diseases such as hypertension, diabetes, hyperthyroidism, and arrhythmia; 2) Suffering from connective tissue diseases such as systemic lupus erythematosus, polymyositis, rheumatoid arthritis, etc. 3) Have a history of blood diseases, severe infections or other systemic diseases; 4) Have taken vasodilator drugs within the past month; 5) Peripheral vascular disease, with arterial occlusion where blood flow signals cannot be detected; 6) Those who are unable to cooperate with the examination. 2. Patients with heart failure complicated with LBBB who are scheduled for CRT treatment: 1) Suffering from connective tissue diseases such as systemic lupus erythematosus, polymyositis, and rheumatoid arthritis; 2) Have a history of blood diseases, severe infections or other systemic diseases; 3) Those who are unable to cooperate with the examination. 3. LBBB patients with LVEF preservation: 1) Suffering from connective tissue diseases such as systemic lupus erythematosus, polymyositis, and rheumatoid arthritis; 2) Have a history of blood diseases, severe infections or other systemic diseases; 3) Those who are unable to cooperate with the examination. 4. Non-lbbb patients with reduced LVEF: 1) Suffering from connective tissue diseases such as systemic lupus erythematosus, polymyositis, and rheumatoid arthritis; 2) Have a history of blood diseases, severe infections or other systemic diseases; 3) Those who are unable to cooperate with the examination.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Global Work Index;Global Constructive Work;Global Wasted Work;Global Work Efficiency;Left ventricular ejection fraction;Left ventricular end-diastolic diameter;Left ventricular end-systolic diameter;Left ventricular end-diastolic volume;Left ventricular end-systolic volume, stroke volume; | — |
Secondary
| Measure | Time frame |
|---|---|
| Systolic pressure;Diastolic pressure;Ascending aortic diameter;Aortic root diameter;Aortic sinus diameter;Sinotubular junction diameter;Interventricular septal thickness;Left atrial anteroposterior, superior-inferior, and lateral diameters;Right atrial superior-inferior and lateral diameters;Main pulmonary artery diameter;Right ventricular area change rate;Inferior vena cava diameter; | — |
Countries
China
Contacts
Public ContactChunyan Ma
The First Hospital of China Medical University
Outcome results
None listed