Obesity
Conditions
Interventions
Esketamine Group:Esketamine for Anesthetic Analgesia
Control group:Conventional Opioid Selection for Analgesia
Sponsors
Zhengzhou Central Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Undergoing ??elective laparoscopic sleeve gastrectomy?; 2. Age between ??18 and 65 years; 3.? ASA physical status class II or III?; 4. Provided written ??informed consent.
Exclusion criteria
Exclusion criteria: 1. Contraindications or allergic reactions to the study medications; 2. Pre-existing severe systemic diseases?? (cardiac, pulmonary, renal, or hepatic); 3. Coagulopathies; 4. Severe psychiatric disorders?? (e.g., schizophrenia, major depression, dementia); 5. History of substance abuse?? (alcohol, opioids, or psychoactive drugs); 6. History of substance abuse?? (alcohol, opioids, or psychoactive drugs); 7. Concurrent participation in another clinical trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Quality of Recovery-15 (QoR-15) score ; | — |
Secondary
| Measure | Time frame |
|---|---|
| Tracheal extubation time??;?Postoperative hospital length of stay;Patient satisfaction score;Patient-controlled analgesia (PCA) attempts Number requiring rescue analgesia Cumulative opioid consumption;heart rate, blood pressure, and SpO2;Numerical Rating Scale (NRS) scores;Agitation-Sedation Scale (RASS) and Verbal Rating Scale (VRS) scores;Quality of Recovery-15 (QoR-15) score ; | — |
Countries
China
Contacts
Public ContactPin Zhang
Zhengzhou Central Hospital
Outcome results
None listed