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Research on the Pathogenic Mechanism of Mannosyltransferase ALG3 Affecting Glycosylation in Extravillous Trophoblasts in Preeclampsia

Research on the Pathogenic Mechanism of Mannosyltransferase ALG3 Affecting Glycosylation in Extravillous Trophoblasts in Preeclampsia

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500115207
Enrollment
Unknown
Registered
2025-12-23
Start date
2026-01-01
Completion date
Unknown
Last updated
2026-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Preeclampsia

Interventions

Preeclampsia patients group:NA
Normal pregnant women group:NA

Sponsors

Hainan Medical College First Affiliated Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 40 Years

Inclusion criteria

Inclusion criteria: 1. Age between 20 and 40 years old, single pregnancy. The diagnostic criteria for preeclampsia are based on the 9th edition of Obstetrics and Gynecology published by People's Health Press. The control group consisted of normal pregnant women who underwent cesarean section delivery. 3. The medical records are complete. 4. All specimen collection requires informed consent and review by the ethics committee of the supporting institution.

Exclusion criteria

Exclusion criteria: 1. Multiple pregnancy; 2. Fetal malformations or chromosomal diseases; 3. Combined with chronic diseases (such as hypertension, chronic kidney disease, autoimmune diseases, etc.) or other serious internal and surgical diseases;

Design outcomes

Primary

MeasureTime frame
Expression of ALG3, INSR, MMP9;—

Countries

China

Contacts

Public ContactZhang Yu

Hainan Medical College First Affiliated Hospital

yudschang@163.com+86 898 66776091

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026