periodontitis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Pathologically confirmed nasopharyngeal carcinoma, receiving primary concurrent chemoradiotherapy, with tumor staging of T1-4 N0-3 M0 and no evidence of distant metastasis; 2.Aged between 18 and 75 years, with a Karnofsky Performance Status (KPS) score of >=60, clear consciousness, and voluntary participation with signed informed consent for the clinical trial.
Exclusion criteria
Exclusion criteria: 1.Presence of other severe systemic diseases that affect periodontal health; 2.History of periodontal treatment within the past year, or continuous use of antibiotics or non-steroidal anti-inflammatory drugs for more than one week within the preceding 3 months; 3.Fewer than 16 natural teeth remaining (excluding root fragments, residual crowns, and third molars); 4.Inability to undergo oral and periodontal health examination due to systemic health conditions or other factors.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Probing pocket depth; | — |
Secondary
| Measure | Time frame |
|---|---|
| Clinical attachment loss;Plaque index;Bleeding index; | — |
Countries
China
Contacts
The First Affiliated Hospital of Fujian Medical University