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Effect of Subgingival Scaling on Oral Health in Nasopharyngeal Carcinoma Patients Undergoing Chemoradiotherapy

Effect of Subgingival Scaling on Oral Health in Nasopharyngeal Carcinoma Patients Undergoing Chemoradiotherapy

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500115187
Enrollment
Unknown
Registered
2025-12-23
Start date
2024-03-23
Completion date
Unknown
Last updated
2026-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

periodontitis

Interventions

Test group:Supragingival Scaling, subgingival Scaling and root Planing
Control group:Supragingival Scaling

Sponsors

The First Affiliated Hospital of Fujian Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1.Pathologically confirmed nasopharyngeal carcinoma, receiving primary concurrent chemoradiotherapy, with tumor staging of T1-4 N0-3 M0 and no evidence of distant metastasis; 2.Aged between 18 and 75 years, with a Karnofsky Performance Status (KPS) score of >=60, clear consciousness, and voluntary participation with signed informed consent for the clinical trial.

Exclusion criteria

Exclusion criteria: 1.Presence of other severe systemic diseases that affect periodontal health; 2.History of periodontal treatment within the past year, or continuous use of antibiotics or non-steroidal anti-inflammatory drugs for more than one week within the preceding 3 months; 3.Fewer than 16 natural teeth remaining (excluding root fragments, residual crowns, and third molars); 4.Inability to undergo oral and periodontal health examination due to systemic health conditions or other factors.

Design outcomes

Primary

MeasureTime frame
Probing pocket depth;

Secondary

MeasureTime frame
Clinical attachment loss;Plaque index;Bleeding index;

Countries

China

Contacts

Public ContactYun Wu

The First Affiliated Hospital of Fujian Medical University

1574316628@qq.com+86 150 0599 0520

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026