FindTrial
Sign In

The application of metagenomic next-generation sequencing in severe pneumonia patients with HSV reactivation

The application of metagenomic next-generation sequencing in severe pneumonia patients with HSV reactivation

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500115181
Enrollment
Unknown
Registered
2025-12-23
Start date
2026-01-01
Completion date
Unknown
Last updated
2026-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Severe pneumonia

Interventions

Observation group of severe pneumonia with herpes simplex virus reactivation:None

Sponsors

Quzhou People Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Age >=18 years old; 2. Conduct mNGS testing; 3. There are results of traditional clinical etiological tests

Exclusion criteria

Exclusion criteria: 1. Missing key clinical data; 2. The patient's family members refused informed consent. 3. The patient's family members requested the termination of the study.

Design outcomes

Primary

MeasureTime frame
The incidence of severe pneumonia caused by HSV reactivation under different immune states based on mNGS results;—

Secondary

MeasureTime frame
Mechanical ventilation time;Semi-quantitative CT scoring;28-day mortality rate;—

Countries

China

Contacts

Public ContactHonglong Fang

Quzhou People Hospital

13022646672@dingtalk.com+86 570 312 5041

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026