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Microneedling with topical insulin and rb-bFGF and rh-aFGF in the treatment of atrophic acne scars

Microneedling with topical insulin and rb-bFGF and rh-aFGF in the treatment of atrophic acne scars

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500115176
Enrollment
Unknown
Registered
2025-12-23
Start date
2024-04-06
Completion date
Unknown
Last updated
2026-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acne scar

Interventions

microneedling:microneedling treatment
microneedling and topical insulin:microneedling and topical insulin treatment
microneedling and rb-bFGF:microneedling and rb-bFGF treatment
microneedling and rh-aFGF:microneedling and rh-aFGF treatment

Sponsors

Tianjin Medical University General Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1) age>=18 years old; 2) atrophic acne scars on the left and right cheeks; 3) Fitzpatrick skin type ?/?; 4) be willing to follow up and agree to the treatment plan.

Exclusion criteria

Exclusion criteria: 1) Active infection at the treatment site; 2) uncontrolled acne vulgaris; 3) patients with a history of hypertrophic scar; 4) received systemic retinoic acid therapy within the past 1 month; 5) having a history of photosensitivity or taking photosensitive drugs; 6) pregnant and lactating women; 7) immunocompromised people, history of skin cancer, recurrent herpes virus infection, malignant tumors, and mental disorders; 8) had a history of chemical exfoliation within 1 month before the study; 9) a history of facial laser treatment in the past 3 months; 10) recent exposure to the sun.

Design outcomes

Primary

MeasureTime frame
Overall reaction rate;VISIA skin texture score;ECCA weight score ;Adverse reactions;Goodman and Baron acne scar grading;;Goodman and Baron acne scar score;Patient satisfaction evaluation;

Countries

China

Contacts

Public ContactShuping Hou

Tianjin Medical University General Hospital

hou-sp1978@163.com+86 138 2115 0956

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Jun 17, 2026