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Dose–Response Relationship Between Frailty and Feeding Intolerance and Functional Prognosis in Critically Ill Older Adults

Dose–Response Relationship Between Frailty and Feeding Intolerance and Functional Prognosis in Critically Ill Older Adults

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500115149
Enrollment
Unknown
Registered
2025-12-23
Start date
2025-12-26
Completion date
Unknown
Last updated
2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Frailty

Interventions

Frail group :N/A
Non-frail group:N/A

Sponsors

Shantou University Medical College
Lead Sponsor

Eligibility

Sex/Gender
All
Age
60 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Age >= 60 years; 2. Expected ICU length of stay >= 72 h; 3. Enteral nutrition initiated within 24–48 h of ICU admission; 4. Enteral nutrition maintained for > 48 h; 5. Informed consent obtained from the patient or family member.

Exclusion criteria

Exclusion criteria: 1. Absolute contraindications to enteral nutrition (e.g., intestinal ischemia or obstruction); 2. End-stage liver disease or cancer cachexia; 3. Total parenteral nutrition for = 3 days prior to ICU admission; 4. Cognitive or psychiatric impairment precluding informed consent.

Design outcomes

Primary

MeasureTime frame
Frailty;Enteral Feeding Intolerance;Activities of Daily Living;

Countries

China

Contacts

Public ContactLiu Yeling

Shantou University Medical College

yelingliu@stu.edu.cn+86 189 2396 3106

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Apr 4, 2026