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Comparison of the clinical efficacy of over-parietal reconstruction and isometric reconstruction in the treatment of anterior cruciate ligament injury: A prospective, multicenter, randomized controlled trial

Comparison of the clinical efficacy of over-parietal reconstruction and isometric reconstruction in the treatment of anterior cruciate ligament injury: A prospective, multicenter, randomized controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500115137
Enrollment
Unknown
Registered
2025-12-23
Start date
2026-01-01
Completion date
Unknown
Last updated
2026-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anterior cruciate ligament injury

Interventions

Isometric reconstruction group:Isometric reconstruction technique
Anterior cruciate ligament overtopping reconstruction Group (Experimental Group):Reconstruction of the anterior cruciate ligament over the top position

Sponsors

Peking University Shenzhen Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Age between 18 and 55 years; 2. ACL rupture confirmed by intraoperative arthroscopy; 3. Accompanied by grade I-II axis displacement; 4. Adolescent patients: If the growth plates are not closed, inclusion is allowed, but preoperative X-rays or MRI must clearly show the bone status, informed consent must be obtained from parents or guardians, and postoperative rehabilitation compliance must be ensured; 5. High-level athletes: Tegner score =7, or professional/semi-professional athletes with formal training and competition experience, and able to ensure standardized rehabilitation and follow-up, with the study goal being return to sport.

Exclusion criteria

Exclusion criteria: 1. Accompanied by posterior cruciate ligament injury, lateral collateral ligament injury, or grade III or higher medial collateral ligament injury; 2. History of knee surgery; 3. Abnormal lower limb alignment; 4. Severe cartilage damage (Outerbridge grade 3 or 4); 5. Patients aged 50–55 with significant degenerative changes in the knee (such as Kellgren–Lawrence grade >=III or MRI cartilage damage >=III); 6. Adolescent patients with severe epiphyseal injury or lower limb deformity; 7. High-level athletes with severe irreparable meniscus injury or multiple ligament injuries; 8. Those unable to complete postoperative rehabilitation training or with poor adherence.

Design outcomes

Primary

MeasureTime frame
The quantitative IKDC score one year after the operation;

Secondary

MeasureTime frame
Vascular and nerve injury;Bone tunnel positioning error/burst;The healing condition of the graft;Lysholm score;Tegner score;Infection of the joint cavity;Deep vein thrombosis;KT2000 Double knee forward relaxation difference and axial shift test;MRI assessment;

Countries

China

Contacts

Public ContactZhang Xintao

Peking University Shenzhen Hospital

zhangxintao@sina.com+86 755 8392 3333

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026