Postoperative Delirium (POD)
Conditions
Interventions
Treatment Group:On the preoperative evening, patients were provided with a semi-liquid diet. Fasting for solid foods commenced at 22:00 (10:00 PM) the night before surgery, take 200 ml of oral electro
Control Group:On the preoperative evening, patients were provided with a semi-liquid diet and began fasting from both solid food and liquids starting at 22:00 the night before the procedure.
Sponsors
Huashan Hospital, Fudan University
Eligibility
Sex/Gender
All
Age
65 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Patients aged 65 years or older, regardless of gender; 2. American Society of Anesthesiologists (ASA) physical status classification of I-III; 3. Scheduled for non-cardiac and non-neurosurgical procedures; 4. No communication barriers and able to comply with all trial protocols.
Exclusion criteria
Exclusion criteria: 1. History of neurological disorders, dementia, or other psychiatric diseases; 2. Preoperative Mini-Mental State Examination (MMSE) score of less than 24 points; 3. History of severe auditory, visual, or motor impairments; 4. Presence of preoperative delirium; 5. Patients with contraindications to oral intake, gastroesophageal reflux, impaired gastric emptying, gastrointestinal obstruction, or history of upper gastrointestinal tumors; 6. History of other severe primary/underlying diseases; 7. Illiteracy or communication barriers; 8. Recent participation in other clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Confusion Assessment Method (CAM); | — |
Secondary
| Measure | Time frame |
|---|---|
| Severity of DeliriumNumber of Delirium Episodes Delirium Subtypes;Pittsburgh Sleep Quality Index;Leeds Sleep Evaluation (LSEQ);Insomnia Severity Index;Physical Function;Cognitive Function;Frailty Score;Postoperation Pain;Postoperative Nausea and Vomiting;YKL-40;Length of Hospital Stay;Quality of Recovery-15 (QoR-15) Score;30-Day Mortality;NfL;ptau217; | — |
Countries
China
Contacts
Public ContactYingwei Wang
Huashan Hospital, Fudan University
Outcome results
None listed