osteochondral lesions of the talus
Conditions
Interventions
Arthroscopic minimally invasive bone grafting combined with PRP injection group:Arthroscopic microfracture combined with cancellous bone grafting and PRP injection
Arthroscopic minimally invasive bone grafting group:Arthroscopic microfracture combined with cancellous bone grafting
Sponsors
Xuzhou Renci Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: (1) Aged between 18 and 60 years; (2) Chronic ankle pain with imaging-confirmed severe osteochondral lesions of the talus; (3) History of unsuccessful conservative treatment (including rest, topical agents, or oral nonsteroidal anti-inflammatory drugs) for at least 3 months; (4) Voluntarily participation in the clinical trial with signed informed consent, and ability to comply with clinical follow-up and provide complete data.
Exclusion criteria
Exclusion criteria: (1) Malalignment of the ankle joint (varus or valgus greater than 5 degrees); (2) Chronic specific synovitis, joint fibrosis, or joint ankylosis resulting in significantly limited range of motion; (3) Moderate to severe osteoarthritis (Takakura stage III or IV); (4) Dysfunction of major organs or severe underlying medical diseases rendering the patient unfit for surgery; (5) Patients with psychiatric or neurological disorders; (6) Pregnant or lactating women, or women planning a pregnancy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| visual anlogue scale, VAS;magneicresonance obseraion of cartlage repair tissue;American Orthopaedic Foot and Ankle Society, AOFAS;Foot and Ankle Outcome Score, FAOS;Ankle Activity Score, AAS; | — |
Countries
China
Contacts
Public ContactGuangchao Cao
Xuzhou Renci Hospital
Outcome results
None listed