Familial hypercholesterolemia, phytosterolemia, mixed hyperlipidemia, etc.
Conditions
Interventions
Gold Standard:Genetic testing and traditional blood lipid testing methods
Index test:Infrared Spectroscopy Measurement
Sponsors
Children's Hospital,Zhejiang University School of Medicine
Eligibility
Sex/Gender
All
Age
No minimum to 60 Years
Inclusion criteria
Inclusion criteria: 1. Presented at the Endocrinology Department of Children's Hospital Affiliated to Zhejiang University School of Medicine for lipid-related testing; 2. Clinically diagnosed with a hereditary dyslipidaemia-related disorder (e.g., phytosterolaemia, hypercholesterolaemia), or identified as a healthy child without associated metabolic abnormalities; 3. Aged between 0 and 18 years.
Exclusion criteria
Exclusion criteria: 1.Those with other serious systemic diseases or metabolic disorders that may interfere with the assessment of blood lipid levels; 2.Recent use (within the past month) of medications that may affect blood lipid levels, such as glucocorticoids; 3.Those whose plasma samples are incomplete or do not meet experimental quality requirements;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Plasma plant sterols;Sensitivity;Accuracy; | — |
Countries
China
Contacts
Public ContactChaochun Zou
Children's Hospital,Zhejiang University School of Medicine
Outcome results
None listed