Hepatitis B associated chronic acute liver failure (HBV-ACLF)
Conditions
Interventions
Group A acute progressive type:N/A
Group B acute recovery type:N/A
Group C slow progressing type:N/A
D group slow recovery type:N/A
Group E slow and persistent type:N/A
The control group compensated hepatitis B cirrhosis:N/A
Sponsors
Tianjin Third Central Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1.Patients aged 18-75 with HBV-ACLF, whose ACLF diagnostic criteria comply with the "Diagnosis and Treatment Guidelines for Liver Failure (2024 Edition)" Diagnostic criteria for acute liver failure. 2.Receives antiviral treatment and artificial liver treatment (2-3 times a week) as well as internal medicine support. 3.Patients with HBV-ACLF who received treatment and were followed up for 90 days with complete data.
Exclusion criteria
Exclusion criteria: 1. Concurrent alcoholic hepatitis, autoimmune hepatitis, genetic metabolic hepatitis 2. Diagnosed or suspected concurrent liver cancer or other malignant tumors; 3.There are serious basic diseases of extrahepatic organs: severe chronic obstructive pulmonary disease with respiratory failure, severe coronary heart disease with heart failure, severe complications of diabetes, chronic kidney disease with renal failure; 4.Clinical information and laboratory examination data are missing or incomplete;Unable to cooperate or refuse to accept follow-up.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| RNA differentially expressed: miRNAs, lncRNAs, and circRNAs; | — |
Countries
China
Contacts
Public ContactLiang Jing
Tianjin Third Central Hospital
Outcome results
None listed