Rheumatoid arthritis, leukoaraiosis
Conditions
Interventions
Sponsors
Xi'an Fifth Hospital
Eligibility
Sex/Gender
All
Age
45 Years to 80 Years
Inclusion criteria
Inclusion criteria: Meets the 2010 ACR/EULAR RA diagnostic criteria; Age>=45 years old; Baseline cranial MRI suggests the presence of LA (Fazekas score >=1); Voluntarily participate in this study and sign a written informed consent form; Expected to complete 1-year follow-up.
Exclusion criteria
Exclusion criteria: There are other immune system diseases or connective tissue diseases besides RA present; Serious internal medical conditions (such as liver and kidney failure, recent myocardial infarction, severe malnutrition, hematological malignancies, etc.) that affect follow-up or evaluation; There are contraindications for MRI examination or inability to cooperate in completing MRI examination; The baseline data is severely missing.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Imaging progression of leukoaraiosis (LA) after 1 year, defined as an increase of =1 point in the Fazekas total score.;Accuracy;Sensitivity;Specificity; | — |
Secondary
| Measure | Time frame |
|---|---|
| Brain MRI examination;Laboratory tests ; | — |
Countries
China
Contacts
Public ContactYe Nan
Xi'an Fifth Hospital
Outcome results
None listed