HIV
Conditions
Interventions
Control group:None
Non-Nucleoside Reverse Transcriptase Inhibitor Group:None
Protease Inhibitor Group:None
Integrase Inhibitor Group:None
Sponsors
Shanghai Public Health Clinical Center
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. All subjects aged >=18 and <=70 years old; 2. Subjects in the HC group must test negative in the initial HIV screening; 3. Subjects in the PLWH group must test positive in the confirmed HIV test or HIV nucleic acid test and must not have previously received antiretroviral therapy.
Exclusion criteria
Exclusion criteria: 1. Symptomatic cardiovascular and cerebrovascular diseases (such as myocardial infarction, heart failure, arrhythmia, cardiomyopathy or vasculitis caused by other reasons, etc.); 2. Other metabolic systemic diseases, such as thyroid insufficiency, adrenal insufficiency, etc.; 3. Drug abuse; 4. Abnormal kidney function (creatinine clearance rate less than 30 ml/min/1.73m^2); 5. Contraindications to CMR (including claustrophobia, metal implants in the body, allergy to gadolinium contrast agents, etc.).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cardiac MRI indicators; | — |
Secondary
| Measure | Time frame |
|---|---|
| Cardiovascular events: heart failure, myocardial infarction, etc.; | — |
Countries
China
Contacts
Public ContactYang Tang
Shanghai Public Health Clinical Center
Outcome results
None listed