Adolescent Depression
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.DSM-V Depression Diagnostic Criteria 2.Individuals who have not received systematic and formal treatment with psychiatric medications, including antidepressants and mood stabilizers, or those who have experienced poor treatment outcomes. 3.HAMD-24 score >24, item 3 >3; Beck Scale for Suicidal Ideation total score =12 4.Individuals who sign the informed consent form
Exclusion criteria
Exclusion criteria: 1.The patient had previously received repetitive transcranial magnetic stimulation (rTMS), vagus nerve stimulation, or electroconvulsive therapy before enrollment. 2.rTMS contraindications: cardiac pacemaker, implanted drug pump, intracardiac metal wire; 3.Acute exacerbation of chronic diseases: such as chronic obstructive pulmonary disease, asthma, hypertension (>140/95 mmHg), heart disease, liver disease, blood disorders, diabetes, tachycardia (resting heart rate >95 beats/min); 4.Neurological diseases: including cerebrovascular diseases, brain tumors, traumatic brain injuries, multiple sclerosis, epilepsy, movement disorders, and migraine during treatment; 5.Currently using respiratory medications, cardiovascular drugs, anticonvulsants, or psychoactive substances; substance abuse and dependence; 6.Depression secondary to general medical conditions or triggering substances; intellectual disability; 7.Unable to locate and quantify the exercise threshold 8. All subjects signed an informed consent form prior to enrolment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| HAMD score; | — |
Countries
CHINA
Contacts
Suzhou Guangji Hospital