Drug-resistant pulmonary tuberculosis
Conditions
Interventions
Control group:Patients with drug-resistant pulmonary tuberculosis who received bedaquiline, lofazimine and moxifloxacin/levofloxacin treatment
TDM intervention group:TDM
Observation group:None
Sponsors
Ningbo First Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1.Patients with drug-resistant pulmonary tuberculosis (WHO 2020 criteria); 2.>= 18 Years old; 3.Accept regimens including bedaquiline, clofazimine, and moxifloxacin/levofloxacin Treatment; 4.Be willing to participate in the research;
Exclusion criteria
Exclusion criteria: 1.Pregnancy or pregnant woman; 2.Those who have recently participated in clinical trials of new drugs; 3.Previous history of heart disease; 4.Severe liver and kidney dysfunction; 5.Mental illness and inability to communicate Power;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of cardiotoxicity; | — |
Secondary
| Measure | Time frame |
|---|---|
| Economic evaluation; | — |
Countries
China
Contacts
Public ContactXu HongBin
Ningbo First Hospital
Outcome results
None listed