Mechanically ventilated patient
Conditions
Interventions
HLT test (+) and SBT test (+):Direct extubation
HLT test (+) and SBT test (-):The research team deliberated whether to proceed with extubation.
Sponsors
The First Affiliated Hospital of USTC, Division of Life Science and Medicine, University of Science and Technology of China
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Age > 18 years old; 2. Receive invasive mechanical ventilation for more than 48 hours; 3. Meet all the screening criteria for aircraft withdrawal: The primary disease is under stable control. PaO2/FiO2 >=150 mmHg (PEEP 8 points; Spontaneous breathing triggers exist.
Exclusion criteria
Exclusion criteria: 1. Cervical spine injury, surgery or restricted movement; 2. Severe neuromuscular diseases (such as high spinal cord injury, amyotrophic lateral sclerosis); 3. Sedative state (RASS > -2 points); 4. Patients with tracheotomy; 5. It is expected that treatment will be abandoned within 24 hours; 6. Patients with consciousness disorders, dementia and other diseases are unable to cooperate.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Head-Lift height;Head-Lift duration;Reintubation rate 48 hours after extubation; | — |
Secondary
| Measure | Time frame |
|---|---|
| Total duration of mechanical ventilation (hours);ICU length of stay (days);28 days of ventilator-free days;28-day all-cause mortality; | — |
Countries
China
Contacts
Public ContactZhou Shusheng
The First Affiliated Hospital of USTC, Division of Life Science and Medicine, University of Science and Technology of China
Outcome results
None listed