Gastrointestinal diseases
Conditions
Interventions
Fospropofol disodium group:None
Sponsors
Guangxi Medical University Cancer Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1: Age >= 18 years and 18 kg/m^2 and <30kg/m^2; 3: ASA class ?-?; 4: Scheduled to undergo painless upper gastrointestinal endoscopic ultrasonography; 5: Voluntarily participate in this study and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1: Known allergy to the investigational drug(s) or any of their components; 2: Severe hepatic insufficiency (Child-Pugh class B or C) or severe renal impairment (estimated glomerular filtration rate [eGFR] = 3), diagnosed sleep apnea syndrome, or severe respiratory disease (e.g., resting SpO2 = 160 mmHg or diastolic blood pressure >= 100 mmHg) or uncontrolled hypotension (systolic blood pressure = III, acute myocardial infarction within the past 6 months); 5: Pregnancy or lactation; 6: Chronic regular use (e.g., > 3 times per week within 4 weeks prior to enrollment) of sedative-hypnotics, opioids, antidepressants, anxiolytics, or antipsychotic medications; 7: Recent history (e.g., within 3 months) of drug or alcohol abuse; 8: The presence of any other condition that may affect the reliable assessment of study outcomes (e.g., communication barriers, inability to cooperate with the required assessments); 9: Exclusively scheduled for transcolonic endoscopic ultrasonography.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Procedure Completion Rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Emergence Time;Incidence of Bradycardia;Total Consumption of the Study Drug;Incidence of Injection Pain;Number of Supplemental Doses of the Study Drug;Incidence of Hypoxemia;Sedation Onset Time;Incidence of Hypotension;Patient Satisfaction;Operator Satisfaction;Incidence of Pruritus;Time to Meet Discharge Criteria;Incidence of Postoperative Nausea and Vomiting; | — |
Countries
China
Contacts
Public ContactFei Lin
Guangxi Medical University Cancer Hospital
Outcome results
None listed