None
Conditions
Interventions
Test group:Patients who received surface anesthesia using Procaine Hydrochloride Injection were administered as follows: 5 ml was given via nebulization before the procedure, and 8 ml was sprayed into
Control group:Patients who received surface anesthesia using Lidocaine Hydrochloride Injection were administered as follows: 5 ml was given via nebulization before the procedure, and 8 ml was sprayed
Sponsors
Chengdu University Affiliated Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18-80 years, regardless of gender; 2. Patients scheduled for elective painless bronchoscopy due to pulmonary disease; 3. American Society of Anesthesiologists (ASA) physical status classification II-III; 4. Willing to sign the informed consent form.
Exclusion criteria
Exclusion criteria: Patients with severe respiratory diseases (e.g., obstructive sleep apnea syndrome, uncontrolled asthma, active massive hemoptysis, severe pulmonary hypertension, etc.); Patients with hemodynamic instability or decompensated heart failure; Patients with epilepsy, severe neurological or psychiatric disorders; Patients with a history of upper respiratory surgery or radiotherapy; Patients allergic to benzodiazepines, opioids, propofol, or other related drugs, or those with contraindications to these medications; Patients allergic to PABA (para-aminobenzoic acid); Patients weighing less than 35 kg; Patients undergoing bronchoscopy via an artificial airway, such as endotracheal intubation or tracheostomy; Patients deemed by the investigator as unsuitable for participation in this trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Coughing rate during surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| Coughing rate after the examination;Patients were assessed using the Visual Analog Scale;The operator performed the Visual Analog Scale assessment.;The degree of glottic opening and closure;Degree of body movement;Changes in vital signs;The usage of ephedrine and atropine; | — |
Countries
China
Contacts
Public ContactLiu Wenjie
Chengdu University Affiliated Hospital
Outcome results
None listed