Atrial fibrillation
Conditions
Interventions
Radiofrequency ablation:The RFA procedure uses the CARTO magnetic-electrical combined mapping system (Biosense Webster, Inc.) or the Ensite three-dimensional electroanatomical mapping system (Saint Ju
Pulsed field ablation:After confirming the successful puncture through angiography, PFA connected the disposable cardiac pulsed electrical field ablation catheter (produced by Shenzhen Huite Medical C
Cryoballoon ablation:During the CBA procedure, patients remain supine and conscious. Puncture sites on the right internal jugular and bilateral femoral veins are disinfected with iodophor, and a steri
Sponsors
The Second Xiangya Hospital of Central South University
Eligibility
Sex/Gender
All
Age
18 Years to 100 Years
Inclusion criteria
Inclusion criteria: (1) There is a clearly recorded AF attack waveform in 12-lead electrocardiogram or a single-lead electrocardiogram lasting for more than 30 seconds; (2) Age is 18 years or older; (3) Planned to undergo RFA, CBA or PFA surgery at this center; (4) Voluntarily signed the informed consent form.
Exclusion criteria
Exclusion criteria: (1) Known cognitive impairment (baseline MoCA score less than 26) or less than 6 years of compulsory education (2) Presence of magnetic resonance contraindications (claustrophobia, history of panic attacks, or presence of non-removable metal devices in the body) (3) Acute coronary syndrome, acute stroke, or having undergone cardiac surgery within 3 months (4) Previous multiple AF ablation history or pacemaker implantation history (5) Severe liver dysfunction and renal dysfunction (6) Any untreated or uncontrolled hyperthyroidism (7) Severe active infection (8) Complicated with severe heart valve disease (9) Pregnant or lactating (10) Had acute myocardial infarction within 3 months before enrollment (11) Left ventricular ejection fraction (LVEF) less than 35% (12) Presence of congenital heart disease, regardless of whether it has been corrected (13) Presence of other arrhythmias requiring ablation treatment (14) Left atrial thrombus (15) Left atrial diameter (LAD) greater than 55mm (long-axis view of the sternum in transthoracic echocardiography) (16) Participating in other clinical trial projects simultaneously (17) Medical staff participating in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Silent cerebral embolism;Cognitive function; | — |
Secondary
| Measure | Time frame |
|---|---|
| Silent cerebral lesion;AF recurrence;Intracranial microbleeds;Overt stroke;Other complications after AF ablation; | — |
Countries
China
Contacts
Public ContactQiming Liu
The Second Xiangya Hospital of Central South University
Outcome results
None listed